Im Serum liegt das PSA meist an andere Proteine (Alpha1-Antichymotrypsin, Alpha1-Antitrypsin, Alpha2-Makroglubulin (Antiproteasen) und Protein C) gebunden vor. Dieses so genannte komplexierte PSA (cPSA) macht einen deutlich größeren Anteil (70-90%) am totalen PSA (tPSA) als das freie - Not bound or unbound to a protein - for PSA (fPSA, 10-30%). When speaking in general but only on the PSA value to the whole or the total PSA meant.
Note
All investigations should be conducted in the same laboratory or to compare two levels of PSA in the time interval should always be the same laboratory tests are used because not all methods of investigation - despite the normal range - measure the same, so that obtained in different laboratories results can not be compared easily and thoughtlessly.
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